Can diaphragm pacing improve gas exchange? Insights from quadriplegic patients.

نویسندگان

  • Jésus Gonzalez-Bermejo
  • Capucine Morélot-Panzini
  • Marjolaine Georges
  • Alexandre Demoule
  • Thomas Similowski
چکیده

Running head: diaphragm pacing and gas exchange One sentence summary: Diaphragm pacing reduces alveolo-arterial gradient and deadspace as compared to positive pressure ventilation in humans.

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Can diaphragm pacing improve gas exchange? Insights from quadriplegic patients

References 1 Glanville AR, Estenne M. Indications, patient selection and timing of referral for lung transplantation. Eur Respir J 2003; 22: 845–852. 2 van der Heide F, Dijkstra G, Porte RJ, et al. Smoking behavior in liver transplant recipients. Liver Transpl 2009; 15: 648–655. 3 Corbett C, Armstrong MJ, Neuberger J. Tobacco smoking and solid organ transplantation. Transplantation 2012; 94: 97...

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Phrenic Nerve Stimulation for Diaphragm Pacing in a Quadriplegic Patient

Chronic hypoventilation due to injury to the brain stem respiratory center or high cervical cord (above the C3 level) can result in dependence to prolonged mechanical ventilation with tracheostomy, frequent nosocomial pneumonia, and prolonged hospitalization. Diaphragm pacing through electrical stimulation of the phrenic nerve is an established treatment for central hypoventilation syndrome. We...

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Diaphragm pacing failure secondary to deteriorated chest wall mechanics: When a good diaphragm does not suffice to take a good breath in

Diaphragm pacing allows certain quadriplegic patients to be weaned from mechanical ventilation. Pacing failure can result from device dysfunction, neurotransmission failure, or degraded lung mechanics (such as atelectasis). We report two cases where progressive pacing failure was attributed to deteriorated chest wall mechanics. The first patient suffered from cervical spinal cord injury at age ...

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Long-Term Ventilatory Support by Diaphragm

Thirty-seven quadriplegic patients with respiratory paralysis were treated by electrical stimulation of the phrenic nerves to pace the diaphragm. Full-time ventilatory support by diaphragm pacing was accomplished in 13 patients. At least half-time support was achieved in 10 others. There were two deaths unrelated to pacing in these two groups. Fourteen patients could not be paced satisfactorily...

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Referred shoulder pain (C4 dermatome) can adversely impact diaphragm pacing with intramuscular electrodes.

Diaphragm pacing is an alternative to mechanical ventilation in patients with high cervical cord damage (>C4 dermatome). It brings clinical benefits and reduces health costs [1–3]. It is also indicated in certain cases of central hypoventilation [4]. Two types of diaphragm pacing devices are commercially available. With intrathoracic phrenic stimulation, electrodes are implanted around the phre...

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عنوان ژورنال:
  • The European respiratory journal

دوره 43 1  شماره 

صفحات  -

تاریخ انتشار 2014